Antibiotic Resistance
The World Health Organisation says that “antibiotic resistance is one of the biggest threats to global health, food security, and development”. The major cause of resistance is over-use of antibiotics, either because they are available without medical prescription or from over-prescribing.
MicroGuide™ is an app to help hospital prescribers select the appropriate antimicrobial drug, by presenting hospital medicine guidelines in a user-friendly way.
MicroGuide™ has the ability to create decision support modules (DSMs) for particular conditions, so that prescribers can answer a series of conditional questions about factors such as disease severity, allergies, resistance risks and pregnancy status to be guided to a recommended choice of drugs or in some cases to seek further microbiology specialist advice.
We are running a randomised controlled trial of MicroGuide DSMs for five common infections (UTI, CAP, HAP, skin and skin structure infection and intra-abdominal infection) to assess the impact on prescribing patterns at the aggregate hospital level. We are not collecting patient or clinician level data.
How to Participate
The study has a favourable NHS ethics review, approval from the Health Research Authority and is on the NIHR portfolio.
The study is funded by Merck Sharp and Dohme (MSD) but has no connection with any of their pharmaceutical products. We are looking for more NHS Trusts to participate in the study.
During the study period, there will be free support from the study team for building comprehensive but simple Decision Support Modules (DSMs) to replace traditional narrative guidelines.
If you would like to express interest or for any further queries please contact our research team via email.
Meet the Team
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- Dr Philip Scott, UWTSD
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- Dr Kieran Hand, NHS England
- Prof Sue Latter, University of Southampton
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- JingXiu Ouyang, Portsmouth Hospitals University NHS Trust
- Dr Kordo Saeed, University Hospital Southampton NHS Foundation Trust
- Yvette Hibberd, Portsmouth Hospitals University NHS Trust
- Prof Paul Rutter, University of Portsmouth
- Dr Ngianga Kandala, University of Portsmouth
- Michaelene Holder-March, UWTSD
Documents
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